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BCL::Commons™ Overview

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BCL::Commons™ (also known as the BioChemistry Library Project) is an object oriented C++ programming library. The library is designed to simulate biological molecules – proteins and peptides in particular – as well as small chemicals such as therapeutics. It comprises mathematical methods to evaluate the energy of these molecules in their natural environment.

Licensing BCL::Commons

Modules of the BCL::Commons suite are available for license via our quick and easy online licensing process.

BCL::Jufo™ Overview

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BCL::Jufo™ is a C++ based application, created by Vanderbilt University's Meiler Laboratory, which is part of a larger library of applications called BCL::Commons. BCL::Jufo predicts secondary structure for a given protein primary sequence. It utilizes an Artificial Neural Network as prediction method. Position-specific scoring matrices from PsiBlast as well as amino acid properties are used as input.

BCL::EMFold™ Overview

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BCL::EMFold™ is a C++ based application, created by Vanderbilt University's Meiler Laboratory, which is part of a larger library of applications called BCL::Commons. BCL::EMFold folds proteins into medium resolution density maps. Secondary structure prediction algorithms are used to predict a pool of helices that correspond to density rods seen in the density map. A Monte Carlo algorithm randomly samples moves that places predicted helices from the pool into these density rods.

BCL::Cluster™ Overview

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BCL::Cluster™ is a C++ based application, created by Vanderbilt University's Meiler Laboratory, which is part of a larger library of applications called BCL::Commons. BCL::Cluster utilizes the Pymol Molecular Graphics System to graphically depict dendrograms in three dimensions. This allows simultaneous display of relevant biological molecules as well as additional information about the clusters and the members comprising them.

BCL::Contact™ Overview

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